Susceptibility of Anopheles gambiae and Anopheles stephensi to tropical isolates of Plasmodium falciparum
نویسندگان
چکیده
منابع مشابه
Plasmodium falciparum-infected Anopheles stephensi inconsistently transmit malaria to humans.
Malaria was transmitted to only 5 of 10 volunteers bitten by 1-2 Anopheles stephensi carrying sporozoites of the 3D7 clone of the NF54 strain of Plasmodium falciparum in their salivary glands. Parasites were detectable by culture in blood taken 7-10 days following exposure and by thick blood film 14-16.5 days after exposure. Infectivity did not correlate with the numbers of sporozoites in the s...
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Transposon-mediated transformation was used to produce Anopheles stephensi that express single-chain antibodies (scFvs) designed to target the human malaria parasite, Plasmodium falciparum. The scFvs, m1C3, m4B7, and m2A10, are derived from mouse monoclonal antibodies that inhibit either ookinete invasion of the midgut or sporozoite invasion of salivary glands. The scFvs that target the parasit...
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Anopheles gambiae is a major vector mosquito for Plasmodium falciparum, the deadly pathogen causing most human malaria in sub-Saharan Africa. Synthesized in the fat body, trehalose is the predominant sugar in mosquito hemolymph. It not only provides energy but also protects the mosquito against desiccation and heat stresses. Trehalose enters the mosquito hemolymph by the trehalose transporter A...
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Introduction: Malaria is still an important health problem in southern Iran. Anopheles stephensi is one of the most important vectors of malaria, especially in urban areas. Because of long time of chemical insecticides against vectors in endemic areas and their potential resistance to such chemicals, it is necessary that vectors continuously to be assessed against susceptibility level. We...
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Chromosome inversions suppress genetic recombination and establish co-adapted gene complexes, or supergenes. The 2La inversion is a widespread polymorphism in the Anopheles gambiae species complex, the major African mosquito vectors of human malaria. Here we show that alleles of the 2La inversion are associated with natural malaria infection levels in wild-captured vectors from West and East Af...
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ژورنال
عنوان ژورنال: Malaria Journal
سال: 2007
ISSN: 1475-2875
DOI: 10.1186/1475-2875-6-139